Faculty: Biography
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Timothy Long, Ph.D. Assistant Professor Pharmaceutical and Biomedical Sciences
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| Biosketch | |||
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| Ph.D. Chemistry | Univ. of South Florida | Tampa | 2003 |
| B.S. Biology | Univ. of South Florida | Tampa | 1999 |
- Post-doctoral Experience
- Research Associate, University of Notre Dame, Notre Dame, IN 2004-2006
- Honors and Awards
- Research Interests
- Major research interests are in the development of new synthetic methodologies that lead to the construction of biologically active molecules with pharmacological properties. Special emphasis is given to peptide-like molecules that may serve as antimicrobial agents or inhibitors of clinically important enzymes.
- Representative Publications
- Lu, X; Long, T.E. “o-Nitrophenyl Sulfoxides: Efficient Precursors for the Mild Preparation of Alkenes,” Journal of Organic Chemistry (2010), 75(1), 249-252.
Patel, S. K.; Long, T. E. “Preparation of vinylglycines by thermolysis of homocysteine sulfoxides,” Tetrahedron Letters (2009), 50(36), 5067-5070.
Wencewicza, T. A.; Möllmann, U; Long, T. E.; Miller, M. J. “Is Drug Release Necessary for Antimicrobial Activity of Siderophore-drug Conjugates? Syntheses and Biological Studies of the Naturally Occurring Salmycin “Trojan Horse” Antibiotics and Synthetic Desferridanoxamine-antibiotic Conjugates,” Biometals (2009).
Chen, D; Falsetti, S. C.; Frezza, M.; Milacic, V.; Kazi, A.; Cui, Q. C; Long, T. E.; Turos, E.; Dou, Q. “Anti-tumor Activity of N-Thiolated β-Lactam Antibiotics,” Cancer Letters (2008), 268, 63-69.
Revell, K.D.; Heldreth. B; Long, T.E.; Jang, S. Turos, E. "N-Thiolated β-lactams: Studies on the mode of action and identification of a primary cellular target in Staphylococcus aureus." Bioorganic & Medicinal Chemistry (2007), 15, 2453-2467.