Faculty: Biography
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Wendy L. Kelly, Ph.D. Associate Professor Chemistry and Biochemistry
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| Biosketch | |||
|---|---|---|---|
| M.S. Pharmaceutical Sci. | University of Wisconsin | Madison, WI | 1998 |
| M.A. Chemistry | Johns Hopkins University | Baltimore, MD | 2000 |
| B.S. Pharmacy | Oregon State University | Corvallis, OR | 1996 |
| Ph.D. Chemistry | Johns Hopkins University | Baltimore, MD | 2004 |
- Post-doctoral Experience
- Postdoctoral Fellow, Harvard Medical School, 2004-2006
- Honors and Awards
- ACS PROGRESS/Dreyfus Lectureship Award, 2008
Needle Assistant Professor Chair, 2007
Camille and Henry Dreyfus New Faculty Award, 2006
Georgia Institute of Technology Institute for Bioengineering and Bioscience Parker H.
Petit Scholar, 2006 to present
Rho Chi – Academic Honor Society in Pharmacy, 1995
Oregon State University Presidential Scholar, 1991-1995
- Research Interests
- Biosynthetic engineering
Biochemistry of polyketide and nonribosomal peptide cross-bridging reactions
Bioorganic chemistry
Enzyme mechanisms
Biosynthesis of medicinal natural products
Secondary metabolism
- Representative Publications
- Wendy L. Kelly, Lisa Pan, and Chaoxuan Li (2009) Thiostrepton Biosynthesis: Prototype for a New Family of Bacteriocins, J. Am. Chem. Soc. 131, 4327-4334.
Kathryn E. Roege and Wendy L. Kelly, Biosynthetic Origins of the Pyrroloketoindane Antibiotic Indanomycin, Org. Lett. 2009, 11, 297-300.
Wendy L. Kelly, Intramolecular Cyclizations of Polyketide Biosynthesis: Mining for a "Diels-Alderase?" Org. Biomol. Chem. 2008, 6, 4483-4493.
Wendy L. Kelly, Michael T. Boyne II, Ellen Yeh, David A. Vosburg, Danica Galonic, Neil L. Kelleher, Christopher T. Walsh (2007) Characterization of the Aminocarboxycyclopropane-forming enzyme CmaC. Biochemistry, 46, 359-368.
Wendy L. Kelly, Nathan J. Hillson, and Christopher T. Walsh (2005) Excision of the Epothilone Synthetase B Cyclization Domain and Demonstration of in trans Condensation/Cyclodehydration Activity, Biochemistry, 44, 13385-13393.