Faculty: Biography

Wendy L. Kelly, Ph.D.
Associate Professor
Chemistry and Biochemistry
Address: Georgia Institute of Technology
901 Atlantic Drive
Atlanta, GA 30332-0400
Office: 3304
Phone: (404) 385-1154
Email: wendy.kelly@chemistry.gatech.edu
Biosketch
M.S. Pharmaceutical Sci.University of WisconsinMadison, WI1998
M.A. ChemistryJohns Hopkins UniversityBaltimore, MD2000
B.S. PharmacyOregon State UniversityCorvallis, OR1996
Ph.D. ChemistryJohns Hopkins UniversityBaltimore, MD2004
Post-doctoral Experience
Postdoctoral Fellow, Harvard Medical School, 2004-2006
Honors and Awards
ACS PROGRESS/Dreyfus Lectureship Award, 2008
Needle Assistant Professor Chair, 2007
Camille and Henry Dreyfus New Faculty Award, 2006
Georgia Institute of Technology Institute for Bioengineering and Bioscience Parker H.
Petit Scholar, 2006 to present
Rho Chi Academic Honor Society in Pharmacy, 1995
Oregon State University Presidential Scholar, 1991-1995
Research Interests
Biosynthetic engineering
Biochemistry of polyketide and nonribosomal peptide cross-bridging reactions
Bioorganic chemistry
Enzyme mechanisms
Biosynthesis of medicinal natural products
Secondary metabolism
Representative Publications
Wendy L. Kelly, Lisa Pan, and Chaoxuan Li (2009) Thiostrepton Biosynthesis: Prototype for a New Family of Bacteriocins, J. Am. Chem. Soc. 131, 4327-4334.

Kathryn E. Roege and Wendy L. Kelly, Biosynthetic Origins of the Pyrroloketoindane Antibiotic Indanomycin, Org. Lett. 2009, 11, 297-300.

Wendy L. Kelly, Intramolecular Cyclizations of Polyketide Biosynthesis: Mining for a "Diels-Alderase?" Org. Biomol. Chem. 2008, 6, 4483-4493.

Wendy L. Kelly, Michael T. Boyne II, Ellen Yeh, David A. Vosburg, Danica Galonic, Neil L. Kelleher, Christopher T. Walsh (2007) Characterization of the Aminocarboxycyclopropane-forming enzyme CmaC. Biochemistry, 46, 359-368.

Wendy L. Kelly, Nathan J. Hillson, and Christopher T. Walsh (2005) Excision of the Epothilone Synthetase B Cyclization Domain and Demonstration of in trans Condensation/Cyclodehydration Activity, Biochemistry, 44, 13385-13393.
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